Cardiology billing is highly complex, and modifiers play a crucial role in clean claims. Missing or misusing modifiers like -26, -TC, -25, -59, X modifiers, or -LT/-RT often leads to denials, delayed cash flow, compliance risks, and revenue loss. Modifiers explain medical necessity, distinguish multiple or repeated procedures, and separate professional from technical components. Accurate use ensures faster payments, fewer denials, and stronger revenue for cardiology practices.